Molecular Typing of Trypanosoma cruzi Isolates, United States
نویسندگان
چکیده
Studies have characterized Trypanosoma cruzi from parasite-endemic regions. With new human cases, increasing numbers of veterinary cases, and influx of potentially infected immigrants, understanding the ecology of this organism in the United States is imperative. We used a classic typing scheme to determine the lineage of 107 isolates from various hosts.
منابع مشابه
Genetic Variation and Exchange in Trypanosoma cruzi Isolates from the United States
Trypanosoma cruzi, the causative agent of Chagas disease, is a multiclonal parasite with high levels of genetic diversity and broad host and geographic ranges. Molecular characterization of South American isolates of T. cruzi has demonstrated homologous recombination and nuclear hybridization, as well as the presence of 6 main genetic clusters or "discrete typing units" (DTUs). Few studies have...
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Early in the history of Chagas disease it became apparent that there was considerable variation in the incidence and severity of infections with parasites classified as being Trypanosoma cruzi (see Pessoa 1960 for a review of early findings by scientists such as Carlos Chagas and Emmanuel Dias). A variety of typing schemes were developed as a means of finding the basis of this variation and mor...
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عنوان ژورنال:
- Emerging Infectious Diseases
دوره 14 شماره
صفحات -
تاریخ انتشار 2008